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Although dementia can affect different areas of the brain, Alzheimer’s disease and frontal temporal dementia affect the cerebral cortex, with Alzheimer’s disease being the most common type of dementia.
It turned out that thicker cortical gray matter generally correlated with better medical outcomes, while thinner gray matter correlated with worse, although the authors note that more research is needed to confirm this biomarker.
It was previously reported that scientists at Massachusetts General Hospital and Boston Children’s Hospital have identified a possible trigger for Alzheimer’s disease. It is a soluble form of aggregated tau protein.